Down Syndrome & Chromosomal Abnormalities Crossword Puzzle

QUESTIONS LIST:

• inversion : a section of the chromosome is broken, upended and reinserted (in the same locus)
• duplication : a section of the chromosome is copied and joined to the chromosome (in the same locus)
• aneuploidy : abnormal number of chromosomes
• deletion : omission of a part/ parts of the chromosome
• translocation : a section of one chromosome is removed and placed on a different chromosome
• trisomy21 : most common form of down syndrome, affecting ~95%
• mosaic : rarest and often mildest, form of down syndrome, affecting ~1%
• robertsonian translocation : type of chromosomal aberration causing down syndrome, which can be inherited
• maternal age : strong risk factor for having a child with down syndrome
• congenital heart disease : leading cause of death amongst infants & young children with down syndrome
• alzheimers : neurodegenerative disease affecting almost all 40+ year olds with the main form of down syndrome
• moro : type of reflex that is impaired in newborns with down syndrome
• clinodactyly : curvature of the 5th finger, often associated with down syndrome
• nuchal translucency : type of ultrasound in-utero screening used to calculate risk of down syndrome