Metabolic Disorders Crossword Puzzle

QUESTIONS LIST:

• bisphosphonates : drugs that inhibit bone resorption, can cause hypocalcaemia.
• vitamind : agonists of nuclear receptors, role in bone metabolism is context-dependent. ( _ _ analogues)
• allopurinol : structural purine analogue, used to lower uric acid, can be hepatotoxic.
• febuxostat : non-purine xanthine oxidase inhibitor, may worsen existing cardiovascular disease.
• probenecid : uricosuric agent, may increase the risk of uric acid kidney stones.
• colchicine : anti-inflammatory drug used in acute gout attacks, reduces vitamin b12 absorption.
• levothyroxine : synthetic form of thyroxine (t4), increases energy expenditure.
• liothyronine : synthetic form of triiodothyronine (t3), increases appetite.
• methimazole : antithyroid drug, higher affinity for tpo than propylthiouracil, nausea likely.
• ptu : antithyroid medication, shorter duration of action than methimazole, can cause liver damage. (abbrev)
• gout : a metabolic disorder characterised by the accumulation of uric acid crystals in joints.
• hypothyroidism : a condition caused by insufficient thyroid hormone production.