Pharmacological Principles Crossword Puzzle

QUESTIONS LIST:

• toxicity : the condition of producing adverse bodily effects due to poisonous qualities of medications. occurs if the peak level of the drug is too high.
• interaction : drug _ is the alteration of one drug by another.
• metabolism : changes a drug to an inactive by-product for excretion. commonly occurs in the liver.
• synergistic : _ effect. two drugs given together that enhance the effects of one another.
• side : _ effect. unintended effects of medication that cause more discomfort rather than harm.
• distribution : the transport of a drug by the bloodstream to it's site of action.
• receptor : once a drug binds to and interacts with the _ a pharmacological response occurs.
• tolerance : needs more medication to get the same effect.
• absorption : the movement of a drug from its site of administration into the bloodstream for distribution to the tissues.
• dependence : a state in which there is a compulsive or chronic need for a drug.
• agonist : a drug that binds to and stimulates the activity of one or more receptors in the body.
• first pass : _ effect. a drug absorbed from the intestine must first pass through the liver before it reaches systemic circulation.
• antagonist : a medication that prevents the activation of a receptor.
• trough : ------ level. the lowest blood level of a drug.
• duration : _ of action. the length of time the drug concentration is sufficient to elicit a therapeutic response.
• action : onset of _ . the time it takes for a drug to elicit a therapeutic response.
• peak : _ level. the highest blood level of a drug.
• excretion : elimination of drugs from the body.
• kidney : the primary organ responsible for excretion.
• adverse : _ drug effects are undesirable effects of a prescribed medication.
• antidote : reverses adverse bodily effects due to poisonous qualities of medications.